CRISPR/cas9-mediated recombination created a 19 bp deletion in the 5' end of exon 2 resulting in a frameshift mutation. Quantitative RT-PCR analysis failed to detect expression in submandibular glands from homozygous mice. (J:290000)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count