Exon 3 was flanked by loxP sites and a FRT-flanked neomycin cassette was inserted downstream of exon 3 before the second loxP site. The selection cassette was removed via flp-mediated recombination leaving exon 3 floxed. (J:298627)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count