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EN
A knockout-first allele was created by the insertion of the following elements into intron 2: an FRT site, splice acceptor sequence , IRES sequence, the lacZ gene, a loxP site a neomycin resistance gene, poly(A) signal sequence, a second FRT site and a second loxP site. A third loxP site was inserted into intron 4. This conditional ready allele was created through removal of the lacZ and neo cassettes by subsequent flp-mediated recombination, leaving exons 3 and 4 floxed. (J:291983)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
