A knockout-first allele was created by the insertion of the following elements into intron 2: an FRT site, splice acceptor sequence , IRES sequence, the lacZ gene, a loxP site a neomycin resistance gene, poly(A) signal sequence, a second FRT site and a second loxP site. A third loxP site was inserted into intron 4. (J:291983)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count