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Exon 2 was disrupted by the insertion of a construct containing IRES-NLS-lacZ followed by a floxed hygromycin selection cassette. The deleted region included nucleotides 2561 through 2860 (amino acids 149-251) encoding encoding the homeodomain and a conserved NK2-specific domain. Expression of beta-galactosidase was driven by the endogenous promoter. Cre-mediated recombination removed the selection cassette. (J:64018)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
