Injection-based targeted transgenesis (PITT) using Gt(ROSA)26Sortm1Maoh replaced the CFP reporter gene with a mouse promoter driving podocyte-specific expression of an EGFP reporter gene. Flp-mediated recombination removed the neomycin resistance cassette. A lox2272 site remains upstream of the promoter. (J:253434)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count