A CAG-loxP-neo-loxP-SCAT1-pA cassette was inserted into the locus. Cre-mediated recombination removed the floxed neo cassette. SCAT1 is a sensor for caspase 1 activation based on FRET (ECFP/Venus). (J:297265)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count