Exon 1 was targeted with two TALENs (GCACCATGCCTGCCTG and AGTAGGAGGCCAGCGGC), resulting in a 17 bp deletion (TCGCCTCTGCTTGCTGG). qRT-PCR and Western blots showed absence of mRNA and protein expression from this allele. (J:293623)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count