The transgene contains an RNU6 promoter, floxed CMV promoter driving ubiquitous expression of an EGFP reporter gene, and a short hairpin RNA targeting Nanog. Cre-expression is required to achieve expression of the shRNA. Line 1 was generated. (J:154977)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count