The transgene contains a superfolder green fluorescent protein inserted in frame into the C-Peptide domain of human proinsulin. The fusion protein cDNA sequence is placed downstream of the murine insulin I (Ins1) promoter and is followed by a 2.5-kb human growth hormone (hGH) minigene that serves as an enhancer. (J:252954)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count