Log In|Sign Up
EN
CRISPR/Cas9 technology used gRNAs (gRNA #1: 5'-GCCACCCCCTCCGAGTGAAG-3' and gRNA #2: 5'-TAGAATCAGAAGCGTGAATT-3') targeting exons 2 and 93 to delete the entire coding region which resulted in a 239,922 bp deletion plus a 4 bp insertion. Western blot analysis confirmed the absence of protein in the testis of homozygous mice. (J:297137)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
