LoxP sites were inserted into introns 1 and 3. An FRT site flanked neomycin resistance gene cassette was inserted between exon 3 and the loxP site. Cre-mediated recombination deleted the neo cassette and left exons 2 and 3 floxed. (J:239950)
Basic Information
(129S6/SvEvTac x C57BL/6NCrl)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count