The promoter drives expression of two deferentially mutated GFP genes (DR-GFP) in hematopoietic cell types. The DR-GFP reporter consists of two mutated GFP genes, SceGFP, which is disrupted at an LweI restriction site by the 18-bp recognition site for the I-SceI endonuclease, and iGFP, which is truncated at both the 5' and 3' ends. (J:104881)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count