Exon 8 was flanked by loxP sites. A neomycin selection cassette flanked by FRT sites was inserted upstream of the second loxP site. Flp-mediated recombination removed the selection marker. (J:294769)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count