The entire coding exon was flanked with loxP sites followed by an nls-LacZ. The original construct also included a floxed neo cassette. Cre-mediated recombination removed the selection cassette. (J:231835)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count