The transgenic construct contains the complete coding region sequence of the mouse Hottip locus under the control of the vav 1 oncogene promoter/control regions (Vav1; from the HS321/45-vav vector). The transgene integrated into chromosome 10 (Chr10:60117191), within the intron between exon 3 and exon 4 of Cdh23 (cadherin 23 (otocadherin) ) gene. (J:282668)