The following elements were inserted into intron 1: a CAG promoter, a loxP site, a neomycin resistance gene cassette, a STOP cassette, a second loxP site, the S. cerevisiae NDI1 gene, an FRT site, an IRES, the EGFP fluorescent marker gene, a second FRT site, the WPRE enhancer and poly(A) signal sequences. This allele will express the inserted gene only after cre-mediated removal of the STOP cassette. (J:296588)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6
Targeted
Insertion
--
--
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3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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