CRISPR/cas9 genome editing is used to delete a 436 bp region that incorporate exon 3 and leads to exon 3 skipping and the production of a nonfunctional mRNA. (J:101977)
Basic Information
NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count