The targeting vector contained a loxP-flanked neo selection cassette in intron 1 and the exon coding for the beta C-terminal variant replacing the gamma variant specific sequence at the 3' end of exon 2. A third loxP site was placed downstream of the beta exon. (J:232822)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count