Exon 2 was targeted with two sgRNAs using CRISPR/Cas9 technology, resulting in a 149 bp deletion. Western blot and immunofluorescence experiments confirmed virtual elimination protein expression from this allele. (J:293924)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count