The targeting construct inserted a reverse tetracycline TransActivator (rtTA) flanked by Lox66 and Lox2272 along with an FRT-flanked puromycin resistance cassette. Flp-mediated recombination removed the selection cassette. (J:268101)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count