The transgenic construct contains the murine IL-22 cDNA under the direction of a liver-specific albumin promoter. Four lines were found to express varying levels of IL-22, with line 8 expressing ~6000 pg/mL IL-22 in serum. (J:294662)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count