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A loxP site, mouse Tardbp DNA binding protein cDNA sequence, an internal ribosome entry site (IRES), an enhanced green fluorescent protein sequence (EGFP), a second loxP site and polyA sequence was inserted between exon 2 and exon 3 of mouse Prnp gene. Founder line 19 was identified with GFP expression in central nervous system and desirable Tardbp expression level/pattern. (J:319624)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
