Exon 3 was flanked with loxP sites. An frt-flanked neomycin selection cassette was removed in ES cells prior to the creation of chimeric mice. Cre-mediated recombination in the germline resulted in the deletion of exon 3. (J:296234)
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Exon 3 was flanked with loxP sites. An frt-flanked neomycin selection cassette was removed in ES cells prior to the creation of chimeric mice. Cre-mediated recombination in the germline resulted in the deletion of exon 3. (J:296234)