Exon 3 was flanked with loxP sites. An frt-flanked neomycin selection cassette was removed in ES cells prior to the creation of chimeric mice. (J:262540)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count