CRISPR/Cas9 technology generated a 1652 bp deletion from chr1:139,254,836-139,256,488, deleting the entire first exon of the B isoform (Crb1-B) and the promoter region. This abolishes the B isoform while preserving other isoforms including the A isoform. (J:293375)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count