A loxP site was inserted upstream of exon 2 and a FRT-flanked selection maker and second loxP site were inserted downstream of exon 2. Flp-mediated recombination removed the selection marker leaving exon 2 floxed. (J:296149)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count