LoxP sites and an frt-flanked neomycin selection cassette were inserted to flank exon 3. The frt-flanked neomycin selection cassette and exon 3 was deleted via FLP and Cre-mediated recombination. (J:278629)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count