Exons 3 to 7 were flanked by loxP sites and an frt-flanked neomycin selection cassette. The neomycin resistance cassette was removed by crossing with CAG-FLPe recombinase transgenic mice. (J:279053)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count