CRISPR/Cas9 genome editing is used to introduce premature stop codons (TAG TAA), a frame shift mutation (A), and a HindIII site (AAGCTT) in to exon 2. (J:296071)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count