CRISPR/Cas9 genome editing technology was used to insert loxP sites in introns 6 and 14. Cre-mediated recombination in the germline resulted in the deletion of exons 7-14. (J:279977)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count