CRISPR/Cas9 genome editing technology was used to generate a deletion of the genomic sequences encoding the Zaplha2 domain of the protein. At the amino acid sequence level,this resulted in a Zalpha2 domain deletion in the encoded protein by joining residues at positions 76 and 151 and deleting residues at positions 77150. (J:295921)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count