LoxP sites were inserted in non-coding regions just 5 to coding exon 1b, and 3 to coding exon 3. An frt-flanked neomycin selection cassette was removed via FLP-mediated recombination. (J:268552)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count