Two loxP sites were inserted flanking exons 2 to 5, and a positive selection neomycin gene flanked by FRT sites was inserted in the intron between exon 1 and 2. The FRT-flanked neomycin selection cassette was deleted via FLP-mediated recombination and exons 2-5 were deleted via Cre-mediated recombination. (J:279191)
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cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count