A loxP site was inserted upstream of exon 4. A loxP site and FRT-flanked neomycin selection cassette was inserted downstream of exon 4. FLP-mediated recombination removed the neomycin selection cassette leaving the loxP sites flanking exon 4. (J:184794)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count