LoxP sites were inserted to flank the minimal promoter and exon 1, which contains the start ATG codon and encode the first 17 amino acids. An frt-flanked neomycin selection cassette was removed via FLP-mediated recombination. Cre-mediated recombination resulted in the deletion of the minimal promoter and exon 1. (J:276877)
Basic Information
(129S6/SvEvTac x C57BL/6NCrl)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count