A loxP site was inserted upstream of the coding region. A loxP and a FRT-flanked neomycin selection cassette were inserted downstream of the coding region. Flp-mediated recombination removed the neomycin selection cassette, leaving the loxP sites flanking the coding region. (J:172134)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count