The targeting vector was designed to replace exons 1, 2a, and 2b with a lacZ gene and a loxP-flanked neomycin selection cassette. The neomycin selection cassette was removed by Cre-mediated recombination. (J:94204)
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The targeting vector was designed to replace exons 1, 2a, and 2b with a lacZ gene and a loxP-flanked neomycin selection cassette. The neomycin selection cassette was removed by Cre-mediated recombination. (J:94204)