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Using CRISPR/Cas9 technology with two sgRNAs targeting the stop codon, a mouse Klra1 cDNA, preceded by sequence for the self-cleaving P2A peptide, was inserted. The insertion replaced the stop codon and the first 32 bp of the 3' UTR. (J:295190)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
