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Exon 2 was targeted using sgRNAs with CRISPR/Cas9 technology. Four different out-of-frame insertion/deletion-insertion allele mouse lines were created, named A15 (TTTAG deletion - AGCT insertion), A20 (AGTCTC deletion -T insertion), AG1 (A insertion), and AG7 (A insertion). (J:295190)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
