The TGATGATAGGATCC sequence, containing three stop codons in frame with the open reading frame and a BamHI restriction site, was inserted into exon 2 using an sgRNA and an ssDNA template with CRISPR/Cas9. (J:294824)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count