An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 13. An additional loxP site was inserted upstream of exon 7. Cre-mediated recombination removed the selection cassette and left exons 7 through 13 floxed. (J:236761)
Basic Information
(C57BL/6 x 129S4/SvJae)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count