Using recombineering with BAC RP23-401E11, the tdTomato red fluorescent gene (including SV40 poly(A) signal sequences) was inserted into exon 1, interrupting the endogenous signal peptide sequence. This creates a reporter knockout allele with the reporter gene driven by the endogenous promoter. (J:294335)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count