The HTGR04004_Z_1_E09 targeting vector inserted an FRT site, lacZ reporter gene, loxP sit, neomycin resistance cassette, FRT site, and loxP site upstream of exon 3. An additional loxP site was inserted downstream of exon 3. Flp-mediated recombination removed the reporter and selection cassette, leaving exon 3 floxed. (J:291033)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count