An FRT site flanked EUCOMM knockout first cassette (splice acceptor-LacZ/betagal-polyA + PGK-NeoR)and a loxP site were inserted into intron 5 and a second loxP site into intron 6. The lacZ and neo cassettes were removed through subsequent flp-mediated recombinatiom, leaving a conditional-ready allele with exon 6 floxed. (J:293922)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6N-Atm1Brd
Targeted
Insertion
--
1
2
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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