The modified chicken beta-actin promoter (CAG) was used to drive ubiquitous expression of a floxed LacZ gene with a triple polyadenylation signal sequence followed by an IRES sequence and the EGFP coding sequence and a poly(A) signal. This allele expresses the beta-galactosidase gene. Only after cre-mediated removal of the LacZ gene will it express the EGFP fluorescent marker gene. (J:109498)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6 x DBA/2)F1
--
Insertion
--
--
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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