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The entire gene sequence (exons and introns) in BAC RP23-240p23 was replaced with a modified rtTA2 sequence (lower bakground activity, higher doxycycline sensitivity and changes to adapt it to eukaryotic cells). This brings the expression of the tetracycline reverse trans-activator under the control of the mouse renin promoter. (J:263308)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
