Velocigene technology was used to replace the tyrosine at position 949 to phenylalanine (Y949F) in exon 21 (TAC to TTC change). A loxP-flanked neomycin selection cassette was removed via cre-mediated recombination. (J:236742)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129S6/SvEvTac x C57BL/6NTac)F1
Targeted
Insertion, Nucleotide substitutions
--
1
2
4

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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