A loxP site and an FRT site flanked neomycin resistance gene cassette were inserted into intron 3 and a second loxP site into intron 6. The neo cassette was removed through subsequent flp-mediated recombination, leaving a conditional-ready allele with exons 4-6 floxed. (J:281205)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count