An FRT site flanked neomycin resistance gene cassette and a loxP site were inserted into intron 14 and a second loxP site downstream of exon 19. The neo cassette was removed through subsequent flp-mediated recombination, leaving a conditional-ready allele with exons 15-19 floxed. (J:292726)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count